Week 5 College Football Parlay: Upset Picks with +2600 Odds

• Our Week 5 CFB parlay features three underdogs on the moneyline
• We’re targeting Northern Illinois, South Florida, and Charlotte for upset potential
• Read below for our best Week 5 college football parlay to bet for Saturday (Sep. 28)

Week 5 of the 2024 college football season brings us a slate of exciting matchups, and what better way to amp up the excitement than by combining some of our top underdog picks into a value-packed CFB parlay?

We’ve crafted a three-team college football parlay that capitalizes on underdog opportunities this weekend. Our Week 5 CFB parlay pays out at +2653 odds, taking advantage of the most undervalued moneylines.

Let’s dive into why these teams have a real shot at pulling off upsets and making our CFB parlay a winner.

CFB Parlay Week 5

All odds as of September 28, at DraftKings Sportsbook. Register with the DraftKings promo code to wager on this Week 5 college football parlay.

Northern Illinois vs NC State

The first leg of our Week 5 college football parlay features Northern Illinois upsetting NC State. The Huskies’ defense ranks 15th nationally, allowing just 256.0 yards per game. They’ve already showed their potential by upsetting Notre Dame in Week 2, holding them to just 14 points.

On offense, running back Antario Brown is a dual-threat playmaker who torched Notre Dame for 99 rushing yards and 126 receiving yards. He’ll be a handful for an NC State defense that has struggled mightily, giving up 51 and 59 points in recent losses to Tennessee and Clemson.

Touchdown Huskies!

Ethan Hampton to Antario Brown for an 83-yard score. Capping a 98-yard touchdown drive for NIU!

NIU 7, ND 7 | 5:35 1st Q | #TheHardWay pic.twitter.com/rRPv677VJb

— NIU Athletics (@NIUAthletics) September 7, 2024

Adding to the Wolfpack’s woes is the uncertain status of quarterback Grayson McCall due to injury. If he can’t go, NC State will rely on an inexperienced backup against NIU’s stout defense. The Huskies’ ability to limit yardage and create turnovers (ranking 21st in Havoc rate) will be crucial in this matchup.

If Northern Illinois can control the clock, avoid costly turnovers, and capitalize on their defensive strengths, they have a real shot at pulling off the road upset and kicking off our college football parlay with a bang.

• Parlay Pick: Northern Illinois ML (+200)

South Florida vs Tulane

The second leg of our college football parlay for Week 5 backs South Florida to upset Tulane. The Bulls’ offense has been firing on all cylinders, averaging an impressive 32.0 points per game. Quarterback Byrum Brown has been efficient, completing 60% of his passes for 771 yards and four touchdowns.

South Florida’s ground game is equally elite, led by the dynamic duo of Kelley Joiner Jr. and Nay’Quan Wright. They’ve combined for 408 rushing yards and six touchdowns while averaging a robust 6.5 yards per carry. This balanced attack should keep Tulane’s defense guessing throughout the game.

Kelley Joiner 50 yard house call!!! pic.twitter.com/XjOP0XXjrf

— SoFloBulls (@SoFloBulls) September 15, 2024

Defensively, the Bulls have been opportunistic, boasting a +6 turnover margin on the year. Tulane, on the other hand, is -1 in that category. If South Florida can force a couple of key takeaways and capitalize on short fields, it could swing the game in their favor.

It’s also worth noting that the Bulls have had Tulane’s number recently, winning three straight in the series, including a 45-31 road victory last season. That confidence and experience in this matchup should be the difference.

• Parlay Pick: South Florida ML (+210)

Charlotte vs Rice

We’re wrapping up our Week 5 college football parlay with Charlotte upsetting Rice. The 49ers are coming off an ugly loss to Indiana that has made them undervalued in the betting market. One week prior, they threw for 340 yards in a win over Gardner-Webb.

Charlotte’s offense has shown flashes of brilliance, especially through the air. Quarterback Trexler Ivey has thrown for 261 yards with three touchdowns and no interceptions so far. Wide receiver Jairus Mack has emerged as a big-play threat, racking up 193 receiving yards on just nine catches.

Trexler.
Ivey.#GoldStandard⛏️ pic.twitter.com/TeX10AIUpk

— Charlotte Football (@CharlotteFTBL) September 15, 2024

If Ivey and Mack can connect for some explosive plays, it will open things up for running back Hahsaun Wilson, who leads the team with 136 rushing yards and a touchdown.

Defensively, the 49ers have some playmakers who can create negative plays. Defensive back Al-Ma’hi Ali leads the charge with 23 tackles and two interceptions. His ability to create turnovers in the secondary could be crucial against a Rice offense that has been inconsistent, averaging only 26 points per game.

While Rice may be favored at home, the Owls are just 1-3 overall and 1-1 against the spread as a favorite of 6.5 points or more this season. Throw the 49ers ML into your Week 5 CFB parlay.

• Parlay Pick: Charlotte ML (+195)

As we head into Week 5 of the college football season, there are some intriguing matchups on the schedule that could lead to some major upsets. For those looking to add some excitement to their Saturday afternoon, taking a shot on a parlay with +2600 odds could pay off big time.

One of the key games to keep an eye on this week is the matchup between the Texas Longhorns and the Oklahoma Sooners. While Oklahoma is currently ranked higher in the polls, Texas has shown flashes of brilliance this season and could pull off the upset. With +2600 odds, including Texas in your parlay could pay off handsomely if they come out on top.

Another game to consider for your parlay is the showdown between the Michigan Wolverines and the Wisconsin Badgers. Michigan has had a strong start to the season, but Wisconsin is always a tough opponent, especially at home. With +2600 odds, including Wisconsin in your parlay could be a smart move if they are able to pull off the upset.

Finally, don’t overlook the matchup between the USC Trojans and the Oregon Ducks. USC has had a rough start to the season, but they have the talent to compete with anyone in the country. Oregon, on the other hand, has been flying under the radar but could surprise some people with a big win. Including either team in your parlay with +2600 odds could lead to a big payday if they come out on top.

In conclusion, Week 5 of college football is shaping up to be an exciting one with plenty of opportunities for upsets. By including some of these underdog teams in your parlay with +2600 odds, you could potentially cash in big time if they are able to pull off the upset. So sit back, relax, and enjoy the games this weekend – you never know what might happen on any given Saturday in college football.