- NFL Week 4 continues with the Chiefs vs Chargers on Sunday afternoon on Sep. 22
- Kansas City is looking to remain undefeated while Los Angeles tries to score a big AFC West win.
- Below, see the Chiefs vs Chargers predictions, expert picks, and where to find the best odds
We get a classic AFC West battle on Sunday afternoon. The Baltimore Ravens (0-2, 0-1 away, 0-2 ATS) head to Arlington for a date with the Dallas Cowboys (1-1, 0-1 home, 1-1 ATS) in Week 3. Kickoff is set for 4:25 pm ET at SoFi Stadium.
The Chiefs won another one-possession game in Atlanta last week and the Chiefs vs Chargers odds favor Kansas City to take a two-game lead in the division. The Chiefs are currently 7-point favorites and are as short as -323 on the moneyline, with the total at 39.5.
Kansas City Chiefs vs Los Angeles Chargers Prediction & Picks
- Chargers +7.0 (-102) at FanDuel
- Over 40 points (-110) at DraftKings
- Chris Wassel’s 2024 NFL picks: 3-0 (+3.00 units)
The Chiefs opened 2024 with one of the higher NFL win totals (double digits again). After three weeks, Kansas City keeps finding ways to win. It may not be pretty but the defending Super Bowl Champions are 3-0. However, they are still a respectable 2-1 ATS. Los Angeles has battled their way to a 2-1 start (also 2-1 ATS).
While some believe that Kansas City could have lost any or all of their first three games, Patrick Mahomes and company did not. That is the bottom line. Even with an off September from Travis Kelce, little has changed for Kansas City. They keep winning even with not the most impressive stats.
The question becomes when does Kansas City’s offense finally start looking like the attack we are accustomed to seeing. If a defense could bring that out, it might just be the Los Angeles Chargers. At least, that is the hope for the sixth-ranked offense in terms of points (25 per game).
Patrick Mahomes whenever he plays in Los Angeles, California:
2,174 Yards (362 YPG)
19 Touchdowns (13 vs LAC)
5 Interceptions (2 vs LAC)All in 6 games. 5-1 record. Undefeated against the Chargers. MaHollywood. https://t.co/qY7jzQL7es pic.twitter.com/zA9YxWIcDm
— Pranav Sriraman (@PranavSriraman) April 9, 2024
The Chargers allowed almost 500 yards last year in that Week 7 contest. One of the biggest debates is that Los Angeles has not faced an offense like the Chiefs (Raiders, Panthers, and Steelers). After that, there is the status of QB Justin Herbert. Herbert has a high-ankle sprain which has bothered him for a few weeks. He tried to play against Pittsburgh last week and Herbert reaggravated the injury. He may be considered a game-time decision with being limited in practice all week.
Los Angeles has given up a mere 33 points but only has scored 58. Now, the Chargers have become kind of a middle-of-the-road offense. This is all while playing a little more intense defensively. Joe Alt and Joey Bosa are definite question marks as well. Bosa has not practiced this week as well. Injuries have truly reared their ugly head when it comes to Los Angeles. It creates a lot of question marks and makes betting a little more of an adventure.
It’s possible the Chargers could bounce back in Week 4 but that depends on Herbert. If he plays, the idea is to go all in on a close game that sees both teams score 20+ points. Again, risking the dollars now in a small way may be the best play for Sunday afternoon.
I expect this is the week we see the Patrick Mahones to Travis Kelce connection to return to some prominence. The expectation is that Los Angeles should just be able to hang in within a score. The Travis Kelce over on receiving yards will be something to keep an eye on along with the Herbert over on yards.
Best Chiefs vs Chargers Odds
As mentioned, the spread still stands at 7.0. Bet365 and BetMGM currently has the best ATS odds on the Chiefs to cover, listing Kansas City at -7 at -115. The best price on the Chargers is +7.0 (-102) via DraftKings, which bettors can use along with these NFL betting strategies.
DraftKings has the best when it comes to the Over of 40 at -110. If one leans Loa Angeles to win outright, they are +300 at FanDuel currently.
Our picks again for this one are the Chargers at +7.0 via DraftKings and the Over of 40 on DraftKings, too.
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The Week 4 matchup between the Kansas City Chiefs and the Los Angeles Chargers is shaping up to be an exciting game with both teams coming off strong performances in the previous weeks. The Chiefs are currently sitting at 2-1, while the Chargers are 1-2, making this game crucial for both teams as they look to solidify their positions in the AFC West.
The Chiefs, led by star quarterback Patrick Mahomes, have been one of the most explosive offenses in the league so far this season. Mahomes has already thrown for over 1,000 yards and 11 touchdowns in just three games, and he will be looking to continue his hot streak against the Chargers’ defense. The Chiefs also have a strong running game with rookie Clyde Edwards-Helaire, who has been a key contributor to their offense.
On the other side of the ball, the Chargers have a solid defense led by pass rusher Joey Bosa. They will need to put pressure on Mahomes and force him into making mistakes if they want to have a chance at winning this game. Offensively, the Chargers will rely on veteran quarterback Tyrod Taylor to lead their offense and make plays against a tough Chiefs defense.
In terms of predictions, the Chiefs are favored to win this game with odds currently sitting at -7.5. The over/under for total points scored is set at 47.5, indicating that this could be a high-scoring affair. While the Chiefs are the favorites, the Chargers have shown that they can compete with top teams in the league and should not be counted out.
Ultimately, this game has all the makings of a close and competitive matchup between two talented teams. It will come down to which team can execute their game plan better and make key plays when it matters most. Fans can expect an exciting game with plenty of scoring opportunities and big plays on both sides of the ball.