Week 2 NFL Odds: Point Spread, Moneyline, and Total for All 16 Games

Week 2 NFL Odds: Point Spread, Moneyline, and Total for All 16 Games

Miami Dolphins quarterback Tua Tagovailoa (1) in action against the Buffalo Bills NFL football game Jan 07, 2024, in Miami Gardens.

  • Odds are starting to be released for NFL Week 2, which runs from Thursday, Sep. 12, to Monday, Sep. 16
  • The Week 2 slate is highlights by the  Buffalo Bills vs Miami Dolphins on Thursday Night Football
  • Below, see the opening NFL Week 2 odds for every game on the schedule

A handful of late-afternoon Week 1 games are still in progress, but oddsmakers have already turned their attention to Week 2 in the NFL, with the odds for more than half of the matchups already posted.

Week 2 starts with a heavyweight AFC East tilt between the Buffalo Bills and Miami Dolphins on Thursday Night Football on Sep. 12 and wraps up with the Atlanta Falcons vs Philadelphia Eagles on Monday, Sep. 16. The other 14 games are all on Sunday, Sep. 15.

The table below lists the opening moneyline, point spread, and game total for every Week 2 NFL game in chronological order. The table will be updated as more Week 2 NFL lines are posted.

NFL Week 2 Odds

Team Moneyline Spread Over/Under Date/Time
Buffalo Bills +102 +1.5 (-110) Over 50.5 (-110) Thursday, Sep. 12
Miami Dolphins -120 -1.5 (-110) Under 50.5 (-110) 8:15 pm ET
Team Moneyline Spread Over/Under Date/Time
New Orleans Saints +235 +6.5 (-110) Over 45.5 (-110) Sunday, Sep. 15
Dallas Cowboys -290 -6.5 (-110) Under 45.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
Tampa Bay Buccaneers +265 +6.5 (-110) Over 48.5 (-110) Sunday, Sep. 15
Detroit Lions -330 -6.5 (-110) Under 48.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
Indianapolis Colts -154 -2.5 (-110) Over 41.5 (-110) Sunday, Sep. 15
Green Bay Packers +130 +2.5 (-110) Under 41.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
New York Jets -230 -4.5 (-110) Over 42.5 (-110) Sunday, Sep. 15
Tennessee Titans +190 +4.5 (-110) Under 42.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
San Francisco 49ers -290 -6.5 (-110) Over 45.5 (-110) Sunday, Sep. 15
Minnesota Vikings +235 +6.5 (-110) Under 45.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
Seattle Seahawks -198 -3.5 (-110) Over 40.5 (-110) Sunday, Sep. 15
New England Patriots +166 +3.5 (-110) Under 40.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
New York Giants +128 +2.5 (-110) Over 42.5 (-110) Sunday, Sep. 15
Washington Commanders -152 -2.5 (-110) Under 42.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
Los Angeles Chargers -240 -4.5 (-110) Over 39.5 (-110) Sunday, Sep. 15
Carolina Panthers +198 +4.5 (-110) Under 39.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
Cleveland Browns +132 +3 (-110) Over 43.5 (-110) Sunday, Sep. 15
Jacksonville Jaguars -156 -3 (-110) Under 43.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
Las Vegas Raiders +360 +8.5 (-110) Over 43.5 (-110) Sunday, Sep. 15
Baltimore Ravens -460 -8.5 (-110) Under 43.5 (-110) 1:00 pm ET
Team Moneyline Spread Over/Under Date/Time
Los Angeles Rams -134 -1.5 (-110) Over 49.5 (-110) Sunday, Sep. 15
Arizona Cardinals +114 +1.5 (-110) Under 49.5 (-110) 4:05 pm ET
Team Moneyline Spread Over/Under Date/Time
Pittsburgh Steelers -154 -2.5 (-110) Over 39.5 (-110) Sunday, Sep. 15
Denver Broncos +130 +2.5 (-110) Under 39.5 (-110) 4:25 pm ET
Team Moneyline Spread Over/Under Date/Time
Cincinnati Bengals +235 +6.5 (-110) Over 47.5 (-110) Sunday, Sep. 15
Kansas City Chiefs -290 -6.5 (-110) Under 47.5 (-110) 4:25 pm ET
Team Moneyline Spread Over/Under Date/Time
Chicago Bears +225 +5.5 (-110) Over 46.5 (-110) Sunday, Sep. 15
Houston Texans -255 -5.5 (-110) Under 46.5 (-110) 8:20  pm ET
Team Moneyline Spread Over/Under Date/Time
Atlanta Falcons +198 +5.5 (-110) Over 48.5 (-110) Monday, Sep. 15
Philadelphia Eagles -240 -5.5 (-110) Under 48.5 (-110) 8:15 pm ET

The early Week 2 NFL odds list the Bills vs Dolphins matchup on TNF with the narrowest spread of the week with Miami opening as just 1.5-point home favorites.

Odds as of Sep. 8 at FanDuel and DraftKings. Get the latest promo code for DraftKings to bet on NFL Week 2. 

Biggest NFL Week 2 Point Spread: Ravens -8.5 vs Raiders

Only one point spread on the board in the Week 2 NFL odds is more than a touchdown, and that comes in the Las Vegas vs Baltimore matchup where the 0-1 Ravens are 8.5-point home favorites over the 0-1 Raiders. Baltimore went toe-to-toe with defending-champion Kansas City on TNF in Week 1 (meaning they’ll have extra time to prepare), coming out on the wrong end of a 27-20 scoreline.

The Raiders, meanwhile, were outclassed 22-10 on the road by the Chargers. New QB Gardner Minshew wasn’t terrible, going 25/33 for 257 yards, one TD, and one interception, but a -3 turnover margin spelled doom for the Silver and Black.

Vikings Big Underdogs to 49ers Despite Impressive Season-Opening Win

If you want proof that oddsmakers are taking the Week 1 results with a grain of salt, look no further than the San Francisco vs Minnesota matchup in the Twin Cities. The Vikings are coming off a resounding 28-6 win on the road against the New York Giants, a game they controlled from start to finish. Yet Minnesota has opened as nearly a touchdown underdog at home to the reigning NFC-champion 49ers.

New starter Sam Darnold was on point, going 19/24 for 208 yards and two touchdowns while spreading the ball around to one of the NFL’s best receiving corps. The Minnesota defense, meanwhile, held the Giants to just 240 total yards of 68 plays (3.5 yards per play) while also generating two interceptions.

San Francisco, which faces Aaron Rodgers and the New York Jets on Monday Night Football tomorrow, will be on a short week.

Harbaugh’s Chargers 4.5-Point Road Favorites at Abysmal Panthers

After a horrendous 2-15 campaign last year, the Carolina Panthers picked up where they left off in Week 1 of 2024, getting embarrassed 47-10 by division-rival New Orleans. Carolina was down 17-0 by the end of the first quarter and trailed 30-0 late in the first half before finally getting on the board.

Sophomore QB Bryce Young showed no growth from his disastrous rookie season, going just 13/30 for 161 yards and two interceptions.

The Chargers, meanwhile, took care of business as 3.5-point home favorites against the Raiders, overcoming an early 7-3 deficit en route to a decisive 22-10 victory in the first game of the Jim Harbaugh era. Former Raven JK Dobbins was absolutely electric spelling Gus Edwards, rushing for 135 yards and a touchdown on just 10 carries, including this 61-yard scamper.

Dobbins went nearly 100 yards over his rushing-yard total of 36.5 in the Week 1 NFL props.

Despite Carolina’s brutal Week 1 showing and LAC’s relatively strong start under Harbaugh, the Chargers have opened Week 2 as relatively slim 4.5-point road favorites against the worst team in the league at the moment.

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As Week 2 of the NFL season approaches, football fans and bettors alike are eagerly anticipating the matchups and odds for all 16 games. From point spreads to moneylines to totals, there are plenty of betting options to consider when placing wagers on the upcoming games.

Let’s take a closer look at the odds for each game in Week 2:

Thursday Night Football kicks off with the New York Giants facing off against the Washington Football Team. The point spread for this game is currently set at Washington -3.5, with a moneyline of -175 for Washington and +155 for the Giants. The total for this game is set at 41.5 points.

On Sunday, the action continues with a full slate of games. Some notable matchups include the Kansas City Chiefs vs. the Baltimore Ravens, with the Chiefs favored by 3.5 points and a moneyline of -175 for Kansas City and +155 for Baltimore. The total for this game is set at 54 points.

Another exciting matchup to watch is the New England Patriots vs. the Seattle Seahawks, with the Seahawks favored by 4 points and a moneyline of -200 for Seattle and +180 for New England. The total for this game is set at 45.5 points.

As the week progresses, odds may shift based on injuries, weather conditions, and other factors that could impact the outcome of the games. It’s important for bettors to stay informed and up-to-date on the latest odds and trends in order to make well-informed decisions when placing bets.

Whether you’re a seasoned bettor or just looking to add some excitement to your football viewing experience, Week 2 of the NFL season offers plenty of opportunities to get in on the action. So grab your favorite snacks, settle in on the couch, and get ready to enjoy some thrilling football games while keeping an eye on the odds and potential betting opportunities.