Week 12 NFL Odds: Spread, Total, and Moneyline for All 13 Games

  • The NFL Week 12 odds have been posted
  • Week 12 is highlighted by the Ravens vs Chargers on MNF
  • Below, see the opening NFL Week 12 odds for all 13 games on the schedule

With two games remaining in Week 11, the opening Week 12 NFL odds have been posted. The Week 12 schedule starts with an AFC North battle between the division-leading Pittsburgh Steelers (8-2) visiting the division-losing Cleveland Browns (2-8) on Thursday Night Football. It culminates with the Baltimore Ravens (7-4) vs LA Chargers (6-3) on MNF with the other 11 games on Sunday. The table below lists the opening odds for all Week 12 games.

Opening NFL Week 12 Odds

Team Spread Moneyline Over/Under Date/Time
Pittsburgh Steelers -5.5 (-110) -238 O 40.0 (-110) Thursday, Nov. 21
Cleveland Browns +5.5 (-110) +195 U 40.0 (-110) 8:15 pm ET
Team Spread Moneyline Over/Under Date/Time
Minnesota Vikings -4.0 (-110) -198 O 40.5 (-110) Sunday, Nov. 24
Chicago Bears +4.0 (-110) +164 U 40.5 (-110) 1 pm ET
Team Spread Moneyline Over/Under Date/Time
Detroit Lions -7.0 (-110) -330 O 49.5 (-110) Sunday, Nov. 24
Indianapolis Colts +7.0 (-110) +265 U 49.5 (-110) 1 pm ET
Team Spread Moneyline Over/Under Date/Time
New England Patriots +7.5 (-115) +295 O 45.5 (-110) Sunday, Nov. 24
Miami Dolphins -7.5 (-105) -375 U 45.5 (-110) 1 pm ET
Team Spread Moneyline Over/Under Date/Time
Tampa Bay Buccaneers -3.0 (-120) -170 O 43.0 (-110) Sunday, Nov. 24
New York Giants +3.0 (-100) +142 U 43.0 (-110) 1 pm ET
Team Spread Moneyline Over/Under Date/Time
Dallas Cowboys +9.5 (-110) +350 O 44.5 (-110) Sunday, Nov. 24
Washington Commanders -9.5 (-110) -455 U 44.5 (-110) 1 pm ET
Team Spread Moneyline Over/Under Date/Time
Kansas City Chiefs -10.5 (-110) -700 O 41.5 (-110) Sunday, Nov. 24
Carolina Panthers +10.5 (-110) +500 U 41.5 (-110) 1 pm ET
Team Spread Moneyline Over/Under Date/Time
Tennessee Titans +7.5 (-110) +295 O 41.5 (-110) Sunday, Nov. 24
Houston Texans -7.5 (-110) -375 U 41.5 (-110) 1 pm ET
Team Spread Moneyline Over/Under Date/Time
Denver Broncos -3.5 (-110) -205 O 40.5 (-110) Sunday, Nov. 24
Las Vegas Raiders +3.5 (-110) +172 U 40.5 (-110) 4:05 pm ET
Team Spread Moneyline Over/Under Date/Time
San Francisco 49ers -1.5 (-102) -104 O 47.5 (-110) Sunday, Nov. 24
Green Bay Packers +1.5 (-120) -112 U 47.5 (-110) 4:25 pm ET
Team Spread Moneyline Over/Under Date/Time
Arizona Cardinals +1.5 (-110) -100 O 47.5 (-110) Sunday, Nov. 24
Seattle Seahawks -1.5 (-110) -118 U 47.5 (-110) 4:25 pm ET
Team Spread Moneyline Over/Under Date/Time
Philadelphia Eagles -2.5 (-115) -148 O 47.0(-110) Sunday, Nov. 24
Los Angeles Rams +2.5 (-105) +124 U 47.0 (-110) 8:20 pm ET
Team Spread Moneyline Over/Under Date/Time
Baltimore Ravens -3.5 (-102) -168 O 48.5 (-110) Monday, Nov. 25
Los Angeles Chargers +3.5 (-120) +142 U 48.5 (-110) 8:15 pm ET

The Falcons, Bills, Bengals, Saints, Jets, and Jaguars are on bye in Week 12.

Odds as of Nov. 17 at DraftKings. See which sports betting payments are available in your area. 

The latest Super Bowl odds continue no longer favor the two-time reigning champion Chiefs. As of Week 11, the Detroit Lions (+400) had inched past KC (+450) at the top of the board.

Biggest Week 12 Spread: Chiefs (-10.5) vs Panthers

The biggest spread in Week 12 is in the perceived mismatch between the Kansas City Chiefs (9-0) and Carolina Panthers (3-7), where the visiting Chiefs are 10.5-point road favorites.

Kansas City appeared headed towards its first L of the season, trailing Buffalo 23-14 in the fourth quarter in Week 11 afternoon action, while the Panthers have won two in a row and are coming off a bye after their Week 9 win over the Giants in London.

The second-biggest spread is in the NFC East battle between the Washington Commanders (7-4) and injury-riddled Dallas Cowboys (3-6), who have lost four in a row. Washington has been listed as a 9.5-point home favorite

Making matters worse for Cooper Rush and the Cowboys, they will also be on a short week after facing Houston on Monday Night Football on Nov. 18.

Highest Week 12 Total: Lions vs Colts (49.5 O/U)

The highest game total in Week 12 is 49.5 in the Detroit Lions (9-1) vs Indianapolis Colts (5-6) matchup. Detroit’s offense continued to cruise in Week 11, putting up its second fifty-burger of the season in a 52-6 rout of the Jacksonville Jaguars.

With Anthony Richardson back under center in place of Joe Flacco, the Colts’ offense had its best game in weeks in Week 11, earning a 28-27 comeback win against the Jets. Richardson was 20-0f-30 for 272 yards, one TD, and no interceptions. His passer rating of 106.5 was his second-highest of his career.

Lowest Week 12 Total: Steelers vs Browns (40.0 O/U)

The lowest total of the week is in the first game on TNF; Steelers vs Browns has opened with a total of just 40.0. The Steelers only had one game go over 40 points in the first five weeks but followed that up with a run of four straight that hit 45 or higher.

Cleveland’s offense has been on fumes the last two weeks (27-10 loss vs LAC, 35-14 loss at NO). While the defense still has a ton of talent, it’s been getting no respite thanks to the offense’s repeated three-and-outs.

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As we head into Week 12 of the NFL season, there are some exciting matchups on the schedule that are sure to keep fans on the edge of their seats. With playoff implications on the line for many teams, every game becomes crucial as we inch closer to the end of the regular season.

Let’s take a look at the odds for all 13 games in Week 12, including the spread, total, and moneyline for each matchup.

Thursday Night Football kicks off with a showdown between the Atlanta Falcons and the New Orleans Saints. The Saints are favored by 6.5 points with an over/under of 50.5 points. The moneyline for this game has the Saints at -275 and the Falcons at +235.

On Sunday, the action continues with a full slate of games. Some notable matchups include the Indianapolis Colts taking on the Tampa Bay Buccaneers. The Buccaneers are favored by 3 points with an over/under of 52 points. The moneyline has the Buccaneers at -165 and the Colts at +145.

Another game to watch is the Green Bay Packers facing off against the San Francisco 49ers. The Packers are favored by 2.5 points with an over/under of 48 points. The moneyline has the Packers at -140 and the 49ers at +120.

In Sunday Night Football, the Baltimore Ravens will take on the Cleveland Browns. The Ravens are favored by 3 points with an over/under of 47.5 points. The moneyline has the Ravens at -160 and the Browns at +140.

Monday Night Football will feature a matchup between the Seattle Seahawks and the Washington Football Team. The Seahawks are favored by 1.5 points with an over/under of 46.5 points. The moneyline has the Seahawks at -125 and Washington at +105.

As always, these odds are subject to change leading up to game time, so be sure to check for any updates before placing your bets. With so much on the line in Week 12, it’s sure to be an exciting weekend of football action.