Betting Preview: Oregon vs Michigan State – Predictions and Betting Odds

  • No.6 Oregon hosts Michigan State in Week 6 CFB action
  • The Ducks are 23.5-point favorites heading into Friday’s clash
  • Check out all our Oregon vs Michigan State picks & predictions

Oregon takes on Michigan State in a newfound Big 10 rivalry on Friday, October 4. The sixth-ranked Ducks are a perfect 4-0 after knocking off UCLA last week, while the 3-2 Spartans are coming off of a 38-7 drubbing at the hands of the Ohio State Buckeyes.

Dive into the Oregon vs Michigan State odds and our best wagers, below.

Oregon vs Michigan State Odds

Team Spread Moneyline Total
Michigan State +23.5 (-110) +1100 Over 52 (-112)
Oregon -23.5 (-110) -2100 Under 52 (-108)

Oregon heads in Friday night’s Big 10 showdown as massive 23.5-point favorites in the latest college football odds. The Michigan State vs Oregon total is currently set at 52 points.

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Odds as of October 2 at DraftKings Sportsbook. Browse the best College Football Betting Apps for Michigan State vs Oregon.

Ducks Look Like CFP Contenders

Oregon’s super powered offense has scored 40 points per game, and rank tenth in points per play this season.

Dillon Gabriel has been spectacular under center, and has looked at home as a Duck. He’s tossed for 1,192 passing yards and nine touchdowns with just one interception while guiding the undefeated Oregon offense. The Oklahoma transfer has averaged 8.8 yards per attempt while completing 81.5 percent of his passes. He’ll be out to show he belongs in the conversation with the biggest names in college football with a statement win against a staple Big 10 program on Friday night.

On the other side of the ball, the Ducks defense have allowed just 4.6 yards per pass, good for fourth in the nation. Oregon has surrendered just 20 points per game, and only 150 passing yards per game so far.

Be aware, Oregon have won 10 straight games in at home in Eugene, but are just 2-5 ATS in their last seven games on Friday’s when playing at home.

Michigan State’s Lousy Offense Holding Team Back

Michigan State’s offense sits just 86th in total yards and 104 in points per game thus far. The Spartans inconsistent ground has put up 132.4 yards per contest.

Most concerningly, Michigan State’s offensive line has struggled in 2024.  They’ve allowed 10 sacks already and 31 tackles for loss. The Spartans sport an awful 45 PFF pass-blocking grade. On top of that, they’ve surrendered 46 pressures leaving quarterback Aidan Chiles out to dry. Chiles has been pressured on 46 drop backs in just five contests.

Defensive coordinator Joe Rossi’s unit has been slightly better than the offense allowing 23.8 points per game (56th), and 4.8 yards per play (34th). Plus, they’ve racked up 35 tackles for loss, 15 sacks (12th in the country) and five interceptions. Despite their opponents otherworldly offense, this Michigan State defense will be ready to play on Friday night. The college football betting trends show that only six percent of the action is on the Spartans.

It’s important to note, Michigan State are 4-2 against the spread in their last six road games. Although, they are an awful 3-9 straight up in their last 12 games as underdogs.

Oregon vs Michigan State Prediction

Michigan State has played half-decent football this season. However, they’ve yet to play an offense of the caliber of Oregon’s. The Ducks are a College Football Playoff contender and will put up plenty of points in this one.

On the other side, the Spartans putrid offense will give bettors pause. Having said that, they’ve scored over 17 points per game, and a few garbage time touchdowns can help get us to the over.

  • Oregon vs Michigan State Pick: Over 52 (-112)

The highly anticipated matchup between the Oregon Ducks and the Michigan State Spartans is set to take place this weekend, and fans and bettors alike are eagerly awaiting the outcome of this exciting game. Both teams are coming off strong performances in their respective season openers, and this game is sure to be a thrilling contest between two top-tier college football programs.

The Oregon Ducks are coming off a dominant 31-24 victory over Fresno State in their season opener. Quarterback Anthony Brown had a solid performance, throwing for 172 yards and two touchdowns, while running back CJ Verdell rushed for 74 yards and a touchdown. The Ducks’ defense also showed promise, holding Fresno State to just 24 points.

On the other side, the Michigan State Spartans are coming off an impressive 38-21 victory over Northwestern in their season opener. Quarterback Payton Thorne had a standout performance, throwing for 185 yards and four touchdowns, while running back Kenneth Walker III rushed for 264 yards and four touchdowns. The Spartans’ defense also played well, holding Northwestern to just 21 points.

In terms of betting odds, the Oregon Ducks are currently listed as 3-point favorites over the Michigan State Spartans. The over/under for total points scored in the game is set at 64.5 points. This suggests that oddsmakers are expecting a close and high-scoring game between these two teams.

When it comes to predictions, this game has all the makings of a close and competitive matchup. Both teams have strong offenses and solid defenses, so it could really go either way. However, the Oregon Ducks have a slight edge in terms of overall talent and experience, which could give them the upper hand in this game.

Ultimately, this game is shaping up to be a must-watch for college football fans and bettors alike. With two talented teams going head-to-head, it’s sure to be a thrilling contest from start to finish. Whether you’re rooting for the Ducks or the Spartans, this game is sure to deliver plenty of excitement and action on the gridiron.