Best Player Prop Bets for Thursday Night Football (Week 15) Matchup between Rams and 49ers

• The LA Rams are in San Francisco to battle the 49ers to kick off Week 15 on TNF
• LA’s Puka Nacua and the 49ers’ Jauan Jennings have the highest receiving yards props
• See all the Rams vs 49ers player props including passing, rushing, receiving, and TD scores for TNF

It’s as close to a must-win as it gets for NFC West rivals if they have any hopes of reaching the postseason, as the LA Rams visit the San Francisco 49ers. Despite LA ripping off six wins in its last eight, the injury-riddled Niners, at 6-7 and bringing a patchwork lineup into this one, enter as 3-point favorites in the Rams vs 49ers odds. Both teams are coming off monster scoring efforts in Week 14, so there’s plenty of choices for our NFL player props. See the full list of Rams vs 49ers player props and odds, below, as well as my top picks.

Rams vs 49ers Player Props

LA’s workhorse back Kyren Williams has the highest rushing yards total at 73.5. Puka Nacua tops all receivers totals with 7.5 receptions and 88.5 receiving yards. Cooper Kupp and Jauan Jennings each have a 5.5 reception line for Thursday. 

 Odds as of Dec 11 at DraftKings Sportsbook. Claim the DraftKings promo code before betting on Rams vs 49ers on TNF.

Rams vs 49ers Player Prop #1: Jennings Receptions

It doesn’t matter how much griping Deebo Samuel has made in the short week, the bottom line is Jennings has emerged as the go-to receiver in the group.

He had seven grabs for 90 yards and two TD’s in last week’s 38-13 thrashing of the Bears, the third time in five games he’s had at least six receptions, missing another by one catch.

Jauan Jennings – All 11 catches from Week 3 at Rams. Would finish with 175 receiving yards, 3 TDs, and 41.0 fantasy points 🤯 pic.twitter.com/33qRUPVv0r

— Kyle Lindemann (@LuckIsMadeFF) September 23, 2024

Jennings was a wrecking ball last time this teams met on Sept 22, hauling in 11 balls for 175 yards and three touchdowns.

With uncertainty at who will be running the ball for the Niners, at least we know where Brock Purdy will be throwing it to.

• Rams vs 49ers Prop Pick: Jennings OVER 5.5 receptions (+115); risk 2 units at DraftKings

LAR vs SF Player Prop #2: Williams Rush Yards

The Rams need balance in their offensive attack, which is why Williams should play a prominent role in this one.

In that 44-42 thriller over the Bills, he had a whopping 29 carries for 87 yards and two touchdowns. He’s topped the 73.5 rush line set for him Thursday three times in the last four games, missing the other by just two yards.

Flip pitch to Kyren Williams for the td 31-14 #RamsHouse pic.twitter.com/ymzmYPzJcX

— George Whipple Jr. (@gwhipp) December 8, 2024

In the first meeting between these teams, Williams carried 24 times, the most totes in a game before Buffalo, running for 89 yards and two scores.

LA’s passing attack gets lots of love, but the ground game does the gritty work to set it all up.

• Rams vs 49ers Prop Picks: Williams OVER 73.5 rushing yards (-105); risk 1 unit at DraftKings

Rams vs 49ers Touchdown Scorer Props

Isaac Guerendo is a game-time decision for San Francisco, but that didn’t stop DraftKings from making him the odds-on favorite to hit paydirt.

Kyren Williams and Patrick Taylor are the other two players with minus odds to score a touchdown.

Rams vs 49ers Player Prop #3: Puka Finds Paydirt

If you’re looking for the big hit, Kyren Williams has scored the first touchdown in each of the Rams’ last three games, and a flier on him doing it a fourth pays out at a nice +500.

You could also have him touching down twice, something he’s done in back-to-back games against ‘Frisco at +330.

For the Niners, Deebo Samuel has scored at least one major in five of his last six against the Rams, while George Kittle has a TD in four of his last five home games vs LA.

We’re riding the hot receiver here: Nacua has scored at least one touchdown in three of the Rams’ last four games.

• Rams vs 49ers Prop Picks: Nakua anytime touchdown (+120); risk 1 unit at DraftKings Sportsbook

Last week: 1-2

This season: 12-23, -11.72 units

As the NFL season heads into Week 15, Thursday Night Football features a matchup between the Los Angeles Rams and the San Francisco 49ers. While the game itself promises to be an exciting battle between two NFC West rivals, there are also plenty of player prop bets to consider for those looking to add some extra excitement to the game.

One player to keep an eye on for the Rams is quarterback Matthew Stafford. Stafford has been having a solid season, throwing for over 3,700 yards and 30 touchdowns so far. One prop bet to consider for Stafford is his passing yards total. The over/under for Stafford’s passing yards in this game is set at 275.5. With the Rams likely to be playing catch-up against a tough 49ers defense, Stafford could easily surpass this total.

Another player to watch for the Rams is wide receiver Cooper Kupp. Kupp has been one of the best receivers in the league this season, leading the NFL in receiving yards and touchdowns. One prop bet to consider for Kupp is his total receiving yards. The over/under for Kupp’s receiving yards in this game is set at 95.5. With Stafford likely to be targeting Kupp early and often, he could easily exceed this total.

On the 49ers side, running back Elijah Mitchell is a player to keep an eye on. Mitchell has emerged as the lead back for San Francisco and has been a key part of their offense. One prop bet to consider for Mitchell is his rushing yards total. The over/under for Mitchell’s rushing yards in this game is set at 75.5. With the 49ers likely to lean heavily on the running game against a vulnerable Rams defense, Mitchell could easily surpass this total.

Overall, there are plenty of player prop bets to consider for Thursday Night Football’s matchup between the Rams and 49ers. Whether you’re looking to bet on passing yards, receiving yards, or rushing yards, there are plenty of opportunities to add some extra excitement to the game. Just be sure to do your research and consider factors such as injuries, matchups, and recent performance before placing your bets.