Predictions, Picks & Odds for Duke vs Northwestern in Friday Night College Football on September 6th

Predictions, Picks & Odds for Duke vs Northwestern in Friday Night College Football on September 6th
Duke Blue Devils quarterback Maalik Murphy goes to hand the ball off too running back Star Thomas

Aug 30, 2024; Durham, North Carolina, USA; Duke Blue Devils quarterback Maalik Murphy (6) goes to hand the ball off too running back Star Thomas (17) against the Elon Phoenix during the second half at Wallace Wade Stadium. Mandatory Credit: James Guillory-USA TODAY Sports

  • Duke vs Northwestern takes place in college football action on Friday night
  • The latest odds have the Wildcats favored by 2.5 points at home
  •  Read below for Duke vs Northwestern odds, prediction and props

Week 2 of the 2024 college football season features an intriguing cross-conference clash, as the Duke Blue Devils (1-0) travel to Evanston to battle the Northwestern Wildcats (1-0) under the Friday night lights.

The Wildcats opened as short 2.5-point home favorites, with the total set at a low 37.5 points. Kickoff from Lanny and Sharon Martin Stadium is set for 9 p.m. ET on FS1.

What’s the best bet for Duke vs Northwestern Friday night football? Let’s dive into my betting pick:

Duke vs Northwestern Prediction

Despite Duke’s five-game win streak in this series, I’m all over the Under in this Week 2 clash. The Blue Devils are in transition with new head coach Manny Diaz and QB Maalik Murphy replacing Mike Elko and Riley Leonard.

Duke’s 26-3 win over FCS foe Elon in Week 1 wasn’t impressive, as the offense struggled, especially in the run game (59 yards). The Blue Devils didn’t pull away until the second half.

YouTube video

Northwestern, meanwhile, rode its strong defense to a gritty 13-6 win over solid Miami-OH in Week 1. The Wildcats held the RedHawks to 40 rush yards, while dual-threat QB Mike Wright threw for 178 yards and ran for 65 and a TD.

The Under has been a strong bet in key trends. In the Wildcats’ last 16 home games as a 3.5 to 10-point favorite, the Under is 14-2. The Under has also hit in five of their last six games and seven of the last 10 meetings with Duke.

Considering the strong Week 1 defensive efforts from both teams, along with the likelihood of inclement weather (wind and possible showers) at Martin Stadium, points should be at a premium on Friday night.

Duke-NW CFB Pick:

  • Under 37.5 Points (-115)

Duke vs Northwestern Odds

Team Spread Moneyline Total
Duke +2.5 (-105) +120 Over 37.5 (-105)
Northwestern -2.5 (-115) -140 Under 37.5 (-115)

Northwestern opened as a 2.5-point home favorite, with moneyline odds of Wildcats -140 and Blue Devils +120. These opening lines suggest an implied probability of 58.3% for a Northwestern win, while Duke’s chances of springing the upset sit at 45.5%.

The total for this contest is set at a relatively low 37 points, which aligns with the impressive defensive performances both teams delivered in Week 1 and the expected weather conditions for Friday night in Evanston.

Notably, sharp bettors have already made an impact, driving the total down from its initial offering of 39.5 to the current number of 37.5. This significant line movement indicates that the wiseguys are anticipating a low-scoring, defensive struggle.

Odds as of Sep. 4, 2024 at ESPN Sportsbook.

Head-to-Head History

Duke has had the upper hand in this series recently, winning and covering the spread in each of the last five meetings. However, the Under has been a prevalent trend when these two teams collide, cashing in seven of their last 10 matchups.

Duke-NW Recent Results

Date Result ATS O/U
09/16/2023 DUKE 38 – NW 14 DUKE -17 Over 48.5
09/10/2022 NW 23 – DUKE 31 DUKE +10 Under 56.5
09/18/2021 DUKE 30 – NW 23 DUKE +2.5 Over 50
09/08/2018 NW 7 – DUKE 21 DUKE +2.5 Under 47.5
09/09/2017 DUKE 41 – NW 17 DUKE +2 Over 54

In their most recent encounter last season, Duke emerged victorious by a score of 38-14. However, with significant changes on the Blue Devils’ sideline and under center, it remains to be seen if they can continue their winning ways against the Wildcats.

Duke vs Northwestern Injury Report

As of now, the only notable injury report for this Week 2 showdown involves Northwestern defensive back Richie Hagarty, who is listed as out.

While Hagarty’s absence may test the depth of the Wildcats’ secondary, it appears that both Duke and Northwestern are otherwise heading into this contest with relatively clean bills of health.

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The highly anticipated matchup between Duke and Northwestern in Friday night college football on September 6th is sure to be a thrilling game for fans of both teams. With both teams coming off strong performances in their season openers, this game is shaping up to be a close and competitive battle.

Duke, coming off a dominant 42-3 victory over North Carolina A&T in their season opener, will look to continue their winning ways against Northwestern. Led by quarterback Quentin Harris, who threw for 345 yards and four touchdowns in the opener, Duke’s offense will look to put up big numbers against a tough Northwestern defense.

On the other side of the ball, Northwestern is coming off a hard-fought 17-7 victory over Stanford in their season opener. The Wildcats’ defense was the standout in that game, holding Stanford to just seven points and forcing three turnovers. Northwestern will look to carry that defensive momentum into their game against Duke and shut down Harris and the Blue Devils’ offense.

In terms of predictions, this game is shaping up to be a close one. Both teams have strong offenses and defenses, making it difficult to predict a clear winner. However, Duke may have a slight edge due to their explosive offense and the momentum they gained from their season opener.

As for picks, Duke may be the safer bet in this matchup. Their offense has the potential to put up big numbers against Northwestern’s defense, and if they can limit turnovers and penalties, they should come out on top. However, Northwestern’s defense is not to be underestimated, and if they can force turnovers and keep Duke’s offense in check, they could pull off the upset.

In terms of odds, Duke is currently favored by 3.5 points in most sportsbooks. The over/under for total points scored in the game is set at 47.5 points. This indicates that oddsmakers are expecting a relatively low-scoring game, with Duke coming out on top by a narrow margin.

Overall, the Duke vs Northwestern matchup on September 6th is sure to be an exciting game for college football fans. With two talented teams facing off in a primetime Friday night showdown, this game has all the makings of a classic battle on the gridiron. Fans can expect a close and competitive game with plenty of action on both sides of the ball.